A case of generalised myasthenia gravis with membranous nephropathy

Abstract

We report a 40-year old woman with bilateral partial ptosis, complete external ophthalmoplegia, and weakness and fatiguability of upper limbs. She was on treatment for hypertension for 5 months at the time of admission. She was found to have generalised myasthenia gravis and membranous nephropathy with end-stage renal disease. Her symptoms and signs improved within 2 months on treatment with neostigmine and prednisolone. It is postulated that either thymic hyperplasia or the subclinical stage of a thymoma may be the underlying aetiological factor in this patient.  

doi:10.4038/cmj.v53i1.224

Ceylon Medical Journal Vol. 53, No. 1, March 2008 pp. 25-26