Xanthogranulomatous Pyelonephritis: a case report

Abstract

Xanthogranulomatous pyelonephritis is a rare debilitating illness which was first described in 1916 by Schlangenhaufer. It ultimately results in diffuse or focal renal destruction and share many features of renal cell carcinoma. Histologically, disease is characterized by lipid laden foamy macrophages

The disease is more common in middle aged females. Most cases are unilateral, and often associated with urinary tract obstructions (Staghorn calculi), urinary tract infections and diabetes. It is commonly associated with Proteus mirabilis and Escherichia coli infections.  

DOI: 10.4038/gmj.v14i1.1189

Galle Medical Journal Vol.14(1) 2009 85-86